1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14295
    Fluvirucin A2
    Inhibitor
    Fluvirucin A2 is an antibiotic against influenza A virus.
    Fluvirucin A2
  • HY-P5550
    Urumin
    Inhibitor
    Urumin has antiviral activity against the human influenza A virus. Urumin inhibits the growth of PR8 influenza virus (IC50: 3.8 μM). Urumin targets the conserved stalk of H1 hemagglutini, and is effective at neutralizing drug-resistant H1 influenza viruses. Urumin protects naive mice from lethal influenza infection.
    Urumin
  • HY-109025AR
    Baloxavir (Standard)
    Inhibitor
    Baloxavir (Standard) is the analytical standard of Baloxavir. This product is intended for research and analytical applications. Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity.
    Baloxavir (Standard)
  • HY-135853R
    Molnupiravir (Standard)
    Inhibitor
    Molnupiravir (Standard) is the analytical standard of Molnupiravir. This product is intended for research and analytical applications. Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.
    Molnupiravir (Standard)
  • HY-N14294
    Fluvirucin A1
    Inhibitor
    Fluvirucin A1 is an antibiotic against influenza A virus.
    Fluvirucin A1
  • HY-161820
    IAV-IN-3
    Inhibitor
    IAV-IN-3 (Compound (R,S)-16s) is an anti-influenza A virus (IAV) agent (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM for MDCK cells). IAV-IN-3 inhibits IAV polymerase with an IC50 of 0.045 μM.
    IAV-IN-3
  • HY-N0699R
    Daphnoretin (Standard)
    Inhibitor
    Daphnoretin (Standard) is the analytical standard of Daphnoretin. This product is intended for research and analytical applications. Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity. Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst.
    Daphnoretin (Standard)
  • HY-163659
    Anti-Influenza agent 6
    Inhibitor
    Anti-Influenza agent 6 (compound 19b) shows inhibitory activity against A/WSN/33/H1N1 (EC50 = 0.015 μM) and influenza B virus Yamagata/16/88 (EC50 = 0.073 μM) and Victotis/2/87 (EC50 = 0.067 μM).
    Anti-Influenza agent 6
  • HY-17015R
    Peramivir trihydrate (Standard)
    Inhibitor
    Peramivir (trihydrate) (Standard) is the analytical standard of Peramivir (trihydrate). This product is intended for research and analytical applications. Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.
    Peramivir trihydrate (Standard)
  • HY-174433
    PAN endonuclease-IN-4
    Inhibitor
    PAN endonuclease-IN-4 (Compound 41) is an inhibitor of PAN endonuclease with antiviral properties. PAN endonuclease-IN-4 is the prodrug of 39-(S). PAN endonuclease-IN-4 can significantly suppress viral replication in an A/WSN/33 infected mouse model.
    PAN endonuclease-IN-4
  • HY-B1080R
    Tilorone dihydrochloride (Standard)
    Inhibitor
    Tilorone (dihydrochloride) (Standard) is the analytical standard of Tilorone (dihydrochloride). This product is intended for research and analytical applications. Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS.Tilorone dihydrochloride exhibits an inhibitory activity with EC50 of 230 nM against Ebola virus (EBOV).
    Tilorone dihydrochloride (Standard)
  • HY-14904AS
    Umifenovir-d6 hydrochloride
    Inhibitor 98.0%
    Umifenovir-d6 (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity.
    Umifenovir-d<sub>6</sub> hydrochloride
  • HY-N9220
    6-Epi-albassitriol
    Inhibitor
    6-Epi-albassitriol can be isolated from Aspergillus sp. FH-A 6357. 6-Epi-albassitriol inhibits the cholesterol synthesis with an inhibition rate of 40% at a concentration of 10 nM in HepG2. 6-Epi-albassitriol exhibits antiviral activity against influenza A virus and parainfluenza virus with MIC of 44.4-133.3 µg/mL.
    6-Epi-albassitriol
  • HY-14818S1
    Laninamivir-13C,15N2
    Inhibitor
    Laninamivir-13C,15N2 (R 125489-13C,15N2) is 13C and 15N labeled Laninamivir. Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively.
    Laninamivir-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-169924
    IAV replication-IN-1
    Inhibitor
    IAV replication-IN-1 (compound 3h) is reduce the upregulation of inflammatory factors and apoptosis induced by IAV infection.alleviate the lung injury caused by IAV infection.
    IAV replication-IN-1
  • HY-N4092R
    Shanziside (Standard)
    Inhibitor
    Shanziside (Standard) is the analytical standard of Shanziside. This product is intended for research and analytical applications. Shanziside is a iridoid glucoside isolated from Phlomis tuberosa L.
    Shanziside (Standard)
  • HY-N14296
    Fluvirucin B1
    Inhibitor
    Fluvirucin B1 is an antibiotic against influenza A virus.
    Fluvirucin B1
  • HY-B0510S3
    Trimethoprim-13C3
    Inhibitor
    Trimethoprim-13C3 is the deuterium labeled Trimethoprim (HY-B0510). Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim-<sup>13</sup>C<sub>3</sub>
  • HY-13317R
    Oseltamivir (Standard)
    Inhibitor
    Oseltamivir (Standard) is the analytical standard of Oseltamivir. This product is intended for research and analytical applications. Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively.
    Oseltamivir (Standard)
  • HY-N15389
    Noformicin
    Inhibitor
    Noformicin has inhibitory effect on mumps virus and Newcastle disease virus in chicken embryo. Noformicin also extended the survival of mice infected with swine, influenza A (PR8) and influenza B (Lee) viruses.
    Noformicin
Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name / Synonyms Application Reactivity